A once-prominent former comedic star of Hollywood has passed away following a lengthy battle against a degenerative disease.

Actress Teri Garr, perhaps best known for her roles in "Young Frankenstein" and "Tootsie," died on Tuesday in Los Angeles, California, at the age of 79, according to Variety.

She is reported to have succumbed to worsening complications of the multiple sclerosis diagnosis that she struggled with for more than two decades.

Multiple sclerosis and a brain aneurysm

The Today Show reported that Garr first went public with her diagnosis of multiple sclerosis, or MS, in 2002, but had likely been suffering from the autoimmune and degenerative neurological condition for potentially decades before that.

She had previously opened up after her diagnosis about experiencing some of the symptoms of MS as early as the 1980s, but noted how those symptoms were often "subtle" and would "come and go" over time, which made it difficult to receive an accurate diagnosis of what ailed her.

In fact, she once claimed to have visited 11 different doctors to discuss her health issues before MS was finally determined to be the cause of her problems in 1999.

Notably, there is no known cure for MS, though there are a variety of treatments that can make it more manageable.

That wasn't Garr's only major health issue, however, as she also suffered a near-fatal brain aneurysm in 2006 that required emergency surgery to stop the bleeding in her brain and left her in a coma for a week, after which she endured months of grueling therapy to learn how to walk and talk again.

Decades-long career in film and TV

According to NBC News, Garr was born in Ohio in 1944 to a vaudeville performer father and a dancer mother but grew up in Los Angeles and trained as a ballet dancer before moving to New York to pursue acting.

Her Hollywood career began in the mid-1960s as a dancer in several Elvis Presley movies and finally began to earn small speaking roles in movies in TV series by the end of that decade. Per Garr's IMDb page, she was ultimately credited with 159 acting appearances in her decades-long career that began in 1963 and continued until 2011.

The highlights of her career included movies like "Young Frankenstein," "Tootsie," "Close Encounters of the Third Kind," and "Mr. Mom," among many others, but she was also prolific on the small screen with one-off appearances in dozens of TV series.

Garr also had several recurring roles in shows like "The Sonny and Cher Comedy Hour," "McCloud," "Fresno," "Good & Evil," "Adventures in Wonderland," "Good Advice," "Women of the House," and "Friends."

She also had 100 credited appearances as herself in various awards shows, specials, talk shows, and TV game shows, hosted "Saturday Night Live" several times, and was a frequent guest of Johnny Carson and David Letterman, along with dozens of appearances as a panelist on "Hollywood Squares."

According to Variety, Garr is survived by her only daughter, Molly O'Neil, and a grandson named Tyryn.