Most of President Donald Trump's nominees for high positions across Washington D.C. have gone off without much of a hitch.

While most of his nominees are already performing their duties, according to the Daily Caller, Trump's nominee for U.S. Attorney is having a difficult time now that a key GOP senator has come out against him. 

Interim U.S. attorney for the District of Columbia Ed Martin, nominated for U.S. Attorney, is facing a serious battle now that Republican North Carolina Sen. Thom Tillis has made it clear he won't support him.

The resistance is causing major backlash within the Republican side of the upper chamber and, not surprisingly, within the White House.

What's going on?

Till told reporters earlier this week that he informed the White House that he will not be voting in favor of Martin as D.C.'s top prosecutor.

"At this point I’ve indicated to the White House I wouldn't support his nomination," Tillis told reporters.

The Daily Caller noted that Tillis cited "disagreements with the interim DC attorney over the January 6th prosecutions while conceding that some J6 defendants were over-prosecuted."

"Where we probably have a difference is that I think anybody that breached the [Capitol] perimeter [on January 6th] should have been in prison for some period of time — whether it’s 30 days or three years is debatable, but I have no tolerance for anybody that entered the building on January 6th and that’s probably where most of the friction was," Tillis said.

While President Trump made a post on Truth Social urging Republican senators to get Martin confirmed, Tillis's holdout position could place the nomination in dire jeopardy.

Tillis, who sits on the Senate Judiciary Committee, is a key vote to break a deadlock on Martin's nomination. If he opposes it, Martin's chances will die in the committee voting process.

Social media reacts

Users across social media weighed in on Tillis' stance against Martin.

"Time to pick the primary challenger. Unavoidable now. NC voters already aren't big fans of Tillis," one X user wrote.

Another X user wrote, "Tillis’ no vote could open door for partisan hack judge Boasberg to make the appointment."

Only time will tell if the White House can change his mind. Hopefully, that's the outcome.